APC Anti-Mouse CD366/Tim-3 Antibody[RMT3-23]

Size

£130.50

Was £145.00

SKU:: E-AB-F1192E
Additional Names:: TIMD3,HAVcr-2,TIM3,TIMD-3
Application:: Flow Cytometry
Storage Conditions:: 2-8[o]C Do not freeze. Protect from light.
Supplier:: Elabscience
Host:: Rat
Reactivities:: Mouse
Buffer:: PBS
Immunogen:: CD366/Tim-3
Clone:: RMT3-23
Uniprot:: Q8VIM0
Synonyms:: CD366;HAVcr-2;hepatitis A virus cellular receptor 2;hepatitis A virus cellular receptor 2 homolog;kidney injury molecule-3;KIM-3;SPTCL;T cell immunoglobulin mucin 3;T-cell immunoglobulin and mucin domain containing 3;T-cell immunoglobulin and mucin domain-containing protein 3;T-cell immunoglobulin mucin family member 3;T-cell immunoglobulin mucin receptor 3;T-cell membrane protein 3;Tim;TIM-;Tim-3;TIM3;Timd;TIMD-3;TIMD3
Extra Details:: CD366 (Tim-3) is a transmembrane protein also known as T cell immunoglobulin and mucin domain containing protein-3. Tim-3 is expressed at high levels on activated T cells (preferentially on Th1 cells, monocytes/macrophages, and dendritic cells). Tim-3 has also been shown to exist as a soluble protein. Cells expressing Tim-3 are present at high levels in the CNS of animals at the onset of experimental autoimmune encephalomyelitis (EAE), a disease mediated by lymphocytes secreting Th1-like cytokines. Tim-3 has been proposed to inhibit Th1-mediated immune responses and promote immunological tolerance.