E-AB-F11920
Purified Anti-Mouse CD366/Tim-3 Antibody[RMT3-23], Functional Grade
Size
£80.10
Was £89.00
- SKU:
- E-AB-F11920
- Additional Names:
- TIM-,Tim3,TIM-3,Timd,Timd3,T-cell membrane protein,T-cell immunoglobulin mucin receptor,T-cell immunoglobulin and mucin domain-containing protein,Tim,TIM-,Tim3,Timd,TIM-3,Timd3,HAVcr-2,Hepatitis A virus cellular receptor 2 homolog,T-cell immunoglobulin and mucin domain-containing protein 3,T-cell immunoglobulin mucin receptor 3,T-cell membrane protein 3,TIMD-3,Havcr2,T cell immunoglobulin and mucin domain containing 3 protein, hepatitis virus cellular receptor 2
- Application:
- Flow Cytometry, Neutralisation
- Concentration:
- >= 1 mg/ml
- Purification:
- protein a/g purified
- Storage Conditions:
- 2-8[o]C Avoid freeze/thaw cycles., -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Host:
- Rat
- Reactivities:
- Mouse
- Buffer:
- Sterile PBS, pH 7.2. < 1.0 EU per mg of the antibody as determined by the LAL method.
- Immunogen:
- Recombinant Mouse CD366 protein
- Clone:
- RMT3-23
- Uniprot:
- Q8VIM0
- Synonyms:
- HAVcr-2;hepatitis A virus cellular receptor 2 homolog;T-cell immunoglobulin and mucin domain containing 3;T-cell immunoglobulin and mucin domain-containing protein 3;T-cell immunoglobulin mucin receptor 3;T-cell membrane protein 3;Tim;TIM-;TIM-3;Tim3;Timd;TIMD-3;Timd3
- Extra Details:
- CD366 (Tim-3) is a transmembrane protein also known as T cell immunoglobulin and mucin domain containing protein-3. Tim-3 is expressed at high levels on activated T cells (preferentially on Th1 cells, monocytes/macrophages, and dendritic cells). Tim-3 has also been shown to exist as a soluble protein. Cells expressing Tim-3 are present at high levels in the CNS of animals at the onset of experimental autoimmune encephalomyelitis (EAE), a disease mediated by lymphocytes secreting Th1-like cytokines. Tim-3 has been proposed to inhibit Th1-mediated immune responses and promote immunological tolerance. None (Azide-Free,Low Endotoxin) are perfectly suited to be used in culture or in vivo (for nonhuman studies) for functional assays blocking, neutralizing, activation or depletion where the presence of azide may damage cells or exogenous endotoxin may signal or activate cells.
- Shipping Conditions:
- Blue Ice