APC Anti-Human CD273/PD-L2 Antibody[24F.10C12]

Size

£115.20

Was £128.00

SKU:: E-AB-F1175E
Additional Names:: CD273PDCD1L2PDL2,B7DC
Application:: Flow Cytometry
Storage Conditions:: 2-8[o]C Do not freeze. Protect from light.
Supplier:: Elabscience
Host:: Mouse
Reactivities:: Human
Buffer:: PBS
Immunogen:: CD273/PD-L2
Clone:: 24F.10C12
Uniprot:: Q9BQ51
Synonyms:: B7 dendritic cell molecule;B7-DC;B7DC;bA574F11.2;Btdc;butyrophilin B7-DC;CD273;PD-1-ligand 2;PD-L2;PDCD1 ligand 2;PDCD1L2;PDL2;programmed cell death 1 ligand 2;programmed death ligand 2
Extra Details:: CD273, known as B7-DC, is also called programmed death ligand 2 (PDL2). This ligand is a 25 kD type I transmembrane protein and a member of B7 family within the immunoglobulin receptor superfamily and is expressed on a subset of dendritic cells, liver and a small subset of macrophages as well as a few transformed cell lines. CD273 has been reported to be stimulatory on dendritic cells when cross-linked and to inhibit T cell activation upon engaging the PD-1 receptor. CD273 has also been reported to bind to an alternative receptor and to mediate T cell activation through such non-PD1 mediated interactions.