APC Anti-Human/Monkey CD39 Antibody[A1]

Size

£108.00

Was £120.00

SKU:: E-AB-F1165E
Additional Names:: ATPDase,CD 39,NTPDase1,SPG64
Application:: Flow Cytometry
Storage Conditions:: 2-8[o]C Do not freeze. Protect from light.
Supplier:: Elabscience
Host:: Mouse
Reactivities:: Human
Buffer:: PBS
Immunogen:: CD39
Clone:: A1
Uniprot:: P49961
Synonyms:: ATPDase;CD39;CD39 antigen;ecto-apyrase;ecto-ATP diphosphohydrolase 1;ecto-ATPase 1;ecto-ATPDase 1;ectonucleoside triphosphate diphosphohydrolase 1;lymphoid cell activation antigen;NTPDase-1;SPG64
Extra Details:: Human CD39 is an integral membrane protein with two transmembrane domains. It exists as a homotetramer. Expression of CD39 is found on activated lymphocytes, a subset of T cells and B cells, and dendritic cells with weak staining on monocytes and granulocytes. CD39 and CD73 have been found on regulatory T cells, specifically the effector/memory like T cells. CD39 can hydrolyze both nucleoside triphosphates and diphosphates. CD39 is the dominant ecto nucleotidase of vascular and placental trophoblastic tissues and appears to modulate the functional expression of type 2 purinergic (P2) G protein coupled receptors (GPCRs). CD39 has intrinsic ecto-ATPase activity. Expression of CD39 is induced on T cells and increased on B cells as a late activation antigen. Product Details