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  2. Monoclonal

E-AB-F11590P

Purified Anti-Human CD197 Antibody[G043H7]

Size

£59.40

Was £66.00

SKU:
E-AB-F11590P
Additional Names:
EBI,CDw,BLR,EVI,CMKBR,CC-CKR,CCR,CCR7,BLR2,CC-CKR-7,CCR-7,CD197,CDw197,CMKBR7,EBI1,EVI1, EBI-1, BLR-2, CMKBR7
Application:
Flow Cytometry
Concentration:
>= 1 mg/ml
Purification:
protein a/g purified
Storage Conditions:
2-8[o]C Avoid freeze/thaw cycles., -20[o]C Avoid freeze/thaw cycles.
Supplier:
Elabscience
Host:
Mouse
Reactivities:
Human
Buffer:
Phosphate-buffered solution, pH 7.2, containing 0.05% non-protein stabilizer. Dialyze to completely remove the stabilizer prior to labeling.
Immunogen:
Recombinant Human CD197 protein
Clone:
G043H7
Uniprot:
P32248
Synonyms:
BLR2;Bukitt's lymphoma receptor 2;C-C chemokine receptor type 7;CC chemokine receptor 7;CC-CKR-7;CCR-7;CD197;CDw197;chemokine (C-C motif) receptor 7;CMKBR7;EBI1;EBV-induced G protein-coupled receptor 1;Epstein-Barr virus induced gene 1;Epstein-Barr virus-induced G-protein coupled receptor 1;lymphocyte-specific G protein-coupled peptide receptor;MIP-3 beta receptor
Extra Details:
The protein encoded by this gene is a member of the G protein-coupled receptor family. This receptor was identified as a gene induced by the Epstein-Barr virus (EBV), and is thought to be a mediator of EBV effects on B lymphocytes. This receptor is expressed in various lymphoid tissues and activates B and T lymphocytes. It has been shown to control the migration of memory T cells to inflamed tissues, as well as stimulate dendritic cell maturation. The chemokine (C-C motif) ligand 19 (CCL19/ECL) has been reported to be a specific ligand of this receptor. Signals mediated by this receptor regulate T cell homeostasis in lymph nodes, and may also function in the activation and polarization of T cells, and in chronic inflammation pathogenesis. Alternative splicing of this gene results in multiple transcript variants.
Shipping Conditions:
Blue Ice