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  2. Monoclonal

E-AB-F11570

Purified Anti-Human CD184 Antibody[12G5], Functional Grade

Size

£80.10

Was £89.00

SKU:
E-AB-F11570
Additional Names:
LCR,CXCR,C-X-C chemokine receptor type,LAP,CD184,D2S201E,FB22,HM89,HSY3RR,LAP-3,LAP3,LCR1,LESTR,NPY3R,NPYR,NPYRL,NPYY3R,WHIM,WHIMS,CXCR4,C-X-C chemokine receptor type 4,Fusin,SDF 1 receptor, Fusin, LESTR,CD184 antigen,Chemokine (C X C motif) receptor 4,Chemokine CXC Motif Receptor 4,C-X-C motif chemokine receptor 4,CXCR-4,CXC-R4,LAP 3,Leukocyte derived seven transmembrane domain receptor,Leukocyte-derived seven transmembrane domain receptor,Lipopolysaccharide associated protein 3,Neuropeptide
Application:
Flow Cytometry
Concentration:
>= 1 mg/ml
Purification:
protein a/g purified
Storage Conditions:
2-8[o]C Avoid freeze/thaw cycles., -20[o]C Avoid freeze/thaw cycles.
Supplier:
Elabscience
Host:
Mouse
Reactivities:
Human
Buffer:
Sterile PBS, pH 7.2. < 1.0 EU per mg of the antibody as determined by the LAL method.
Immunogen:
Recombinant Human CD184 protein
Clone:
12G5
Uniprot:
P61073
Synonyms:
C-X-C chemokine receptor type 4;CD184;CD184 antigen;chemokine (C-X-C motif) receptor 4;D2S201E;FB22;fusin;HM89;HSY3RR;LAP-3;LAP3;LCR1;LESTR;leukocyte-derived seven transmembrane domain receptor;lipopolysaccharide-associated protein 3;LPS-associated protein 3;neuropeptide Y receptor Y3;neuropeptide Y3 receptor;NPY3R;NPYR;NPYRL;NPYY3R;SDF-1 receptor;seven transmembrane helix receptor;seven-transmembrane-segment receptor, spleen;stromal cell-derived factor 1 receptor;WHIM;WHIMS;WHIMS1
Extra Details:
This gene encodes a CXC chemokine receptor specific for stromal cell-derived factor-1. The protein has 7 transmembrane regions and is located on the cell surface. It acts with the CD4 protein to support HIV entry into cells and is also highly expressed in breast cancer cells. Mutations in this gene have been associated with WHIM (warts, hypogammaglobulinemia, infections, and myelokathexis) syndrome. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. None (Azide-Free,Low Endotoxin) are perfectly suited to be used in culture or in vivo (for nonhuman studies) for functional assays blocking, neutralizing, activation or depletion where the presence of azide may damage cells or exogenous endotoxin may signal or activate cells.
Shipping Conditions:
Blue Ice