APC Anti-Human CD161 Antibody[HP-3G10]

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£115.20

Was £128.00

SKU:: E-AB-F1155E
Additional Names:: NKRP1A,CLEC5B,HNKR-P1a,KLRB1,NKR-P1A
Application:: Flow Cytometry
Storage Conditions:: 2-8[o]C Do not freeze. Protect from light.
Supplier:: Elabscience
Host:: Mouse
Reactivities:: Human
Buffer:: PBS
Immunogen:: CD161
Clone:: HP-3G10
Uniprot:: Q12918
Synonyms:: C-type lectin domain family 5 member B;CD161;CLEC5B;hNKR-P1A;killer cell lectin-like receptor subfamily B member 1;killer cell lectin-like receptor subfamily B, member 1;natural killer cell surface protein P1A;NKR;NKR-P1;NKR-P1A;NKRP1A
Extra Details:: CD161 is a type II transmembrane glycoprotein, also known as NKR-P1A, that is expressed as a 40-44 kD homodimer. It is a member of the C-type lectin superfamily. CD161 is expressed on a majority of NK cells, NKT cells, and subsets of peripheral T cells and CD3+ thymocytes. It has been reported that Th17 cells are a subpopulation of CD4+CD161+CCR6+ cells. While the biological function of CD161 is not clear, it has been suggested to serve either as a stimulatory receptor or to inhibit NK cell-mediated cytotoxicity and cytokine production. LLT-1 (lectin-like transcript-1, also named as osteoclast inhibitory lectin or CLEC2D) is the ligand of CD161.