APC Anti-Human CD122/IL-2RB Antibody[TU27]

Size

£120.60

Was £134.00

SKU:: E-AB-F1151E
Additional Names:: CD122,IL-2RB,IL-2RB Beta,Interleukin-2 receptor subunit beta,p75
Application:: Flow Cytometry
Storage Conditions:: 2-8[o]C Do not freeze. Protect from light.
Supplier:: Elabscience
Host:: Mouse
Reactivities:: Human
Buffer:: PBS
Immunogen:: CD122
Clone:: TU27
Uniprot:: P14784
Synonyms:: CD122;CD122 antigen;high affinity IL-2 receptor beta subunit;high affinity IL-2 receptor subunit beta;IL-2 receptor subunit beta;IL-2R subunit beta;IL-2RB;IL15RB;IMD63;interleukin 15 receptor, beta;interleukin 2 receptor, beta;interleukin-15 receptor subunit beta;interleukin-2 receptor subunit beta;P70-75;p75
Extra Details:: CD122 is a 70-75 kD type I transmembrane glycoprotein and member of the Ig superfamily. It is IL-2 receptor B Beta chain also known as IL-2RB Beta, which is also shared by the IL-15 receptor. CD122 is constitutively expressed by NK cells and at lower levels by a subset of T cells. Its expression is upregulated upon activation. The IL-2RB Beta chain can combine with either the common G Gamma subunit (G Gammac, CD132) alone or with the G Gammac subunit and the IL-2RA Alpha subunit (CD25) to generate intermediate or high affinity IL-2 receptor complexes, respectively. CD122 expression levels can be upregulated by activation.