E-AB-F1132E
APC Anti-Mouse CD274/PD-L1 Antibody[10F.9G2]
Size
£83.70
Was £93.00
- SKU:
- E-AB-F1132E
- Additional Names:
- B7H1PD-L1PDCD1L1PDCD1LG1PDL1,B7 homolog 1,B7-H,B7-H1,Programmed cell death ligand 1
- Application:
- Flow Cytometry
- Storage Conditions:
- 2-8[o]C Do not freeze. Protect from light.
- Supplier:
- Elabscience
- Host:
- Rat
- Reactivities:
- Mouse
- Buffer:
- PBS
- Immunogen:
- CD274/PD-L1
- Clone:
- 10F.9G2
- Uniprot:
- Q9EP73
- Synonyms:
- A530045L16Rik;B7 homolog 1;B7h1;PD-;PDCD1 ligand 1;Pdcd1l;Pdcd1l1;Pdcd1lg1;Pdl1;programmed cell death 1 ligand 1
- Extra Details:
- CD274, also known as B7-H1 or programmed death ligand 1 (PD-L1), is a 40 kD type I transmembrane protein and a member of the B7 family within the immunoglobulin receptor superfamily. It is expressed on T cells, B cells, NK cells, dendritic cells, IFN-G Gamma activated endothelial cells, and monocytes. B7-H1 is one of the ligands of PD-1. The interaction of B7-H1 with PD-1 plays an important role in the inhibition of T cell responses. Other studies have shown that B7-H1 is able to costimulate T cell growth and cytokine production. CD274 is involved in costimulation essential for T cell proliferation and production of IL-10 and IFN-G Gamma, in an IL-2-dependent and a PD-1-independent manner. Its interaction with PD-1 inhibits T cell proliferation and cytokine production.
- Shipping Conditions:
- Blue Ice