E-AB-F11240
Purified Anti-Mouse TCR G Gamma/D Delta Antibody[UC7-13D5], Functional Grade
Size
£80.10
Was £89.00
- SKU:
- E-AB-F11240
- Additional Names:
- G Gamma/D Delta TCR,TCR-G Gamma/D Delta
- Application:
- Flow Cytometry
- Concentration:
- >= 1 mg/ml
- Storage Conditions:
- 2-8[o]C Avoid freeze/thaw cycles., -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Host:
- Hamster
- Reactivities:
- Mouse
- Buffer:
- Sterile PBS, pH 7.2. < 1.0 EU per mg of the antibody as determined by the LAL method.
- Clone:
- UC7-13D5
- Extra Details:
- T cell receptor (TCR) is a heterodimer consisting of an A Alpha and a B Beta chain (TCR A Alpha/B Beta) or a G Gamma and a D Delta chain (TCR G Gamma/D Delta). TCR G Gamma/D Delta belongs to the immunoglobulin superfamily, involved in the recognition of certain bacterial and tumor antigens bound to MHC class I. The TCR G Gamma/D Delta associates with CD3 and is expressed on a T cell subset found in the thymus, the intestinal epithelium, and the peripheral lymphoid tissues and peritoneum. Most G Gamma/D Delta T cells are CD4-/CD8-, some are CD8+. T cells expressing the TCR G Gamma/D Delta have been shown to play a role in oral tolerance, tumor-associated tolerance, and autoimmune disease. It has been reported that G Gamma/D Delta T cells also play a principal role in antigen presentation. Immobilized UC7-13D5 antibody has been reported to activate TCR-G Gamma/D Delta-bearing T cells in vitro, and to deplete peripheral TCR-G Gamma/D Delta-bearing T cells in vivo. None (Azide-Free,Low Endotoxin) are perfectly suited to be used in culture or in vivo (for nonhuman studies) for functional assays blocking, neutralizing, activation or depletion where the presence of azide may damage cells or exogenous endotoxin may signal or activate cells.
- Shipping Conditions:
- Blue Ice