E-AB-F11150
Purified Anti-Mouse CD119 Antibody[GR-20], Functional Grade
Size
£80.10
Was £89.00
- SKU:
- E-AB-F11150
- Additional Names:
- Interferon gamma receptor 1,IFNGR1,INGR1,IFN-gamma receptor 1,IFN-gamma-R1,CDw119,Interferon gamma receptor alpha-chain,IFN-gamma-R-alpha,CD119,CDw,IFN-gamma-R,IFN gamma receptor,IFN-gamma receptor,immune interferon receptor,INGR,IFN-G Gamma R,CD119,CD119 antigen,CDw119,Ifgr,IFN gamma receptor 1,IFN-gamma receptor 1,IFN-gammaR,IFN-gamma-R1,IFN-gamma-R-alpha,IFN-G Gamma R1,immune interferon receptor 1,INGR1,Interferon gamma receptor 1,Interferon gamma receptor alpha-chain,interferon-gamma
- Application:
- Flow Cytometry
- Concentration:
- >= 1 mg/ml
- Purification:
- protein a/g purified
- Storage Conditions:
- 2-8[o]C Avoid freeze/thaw cycles., -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Host:
- Rat
- Reactivities:
- Mouse
- Buffer:
- Sterile PBS, pH 7.2. < 1.0 EU per mg of the antibody as determined by the LAL method.
- Immunogen:
- Recombinant Mouse CD119 protein
- Clone:
- GR-20
- Uniprot:
- P15261
- Synonyms:
- CD119;If;Ifgr;IFN-g;IFN-gamma receptor 1;IFN-gamma-R-alpha;IFN-gamma-R1;IFN-gammaR;Ifngr;INF-g receptor;interferon gamma receptor 1;interferon gamma receptor alpha-chain;Nk;Nktar
- Extra Details:
- CDw119 is a 90 kD immunoglobulin superfamily member, also known as IFN-G GammaRA Alpha chain. It is a class II cytokine receptor family member that serves as a IFN-G Gamma-binding chain associated with the IFN-G Gamma B Beta chain also known as AF-1. In addition to ligand binding, CDw119 participates in ligand trafficking. CDw119 is expressed on T and B cells, NK cells, fibroblasts, endothelial, and epithelial cells. Binding of IFN-G Gamma induces receptor dimerization, internalization, Jak1 and Jak2 protein kinase activation and, ultimately, STAT1 activation. IFN-G Gamma initiates and regulates a variety of immune responses. None (Azide-Free,Low Endotoxin) are perfectly suited to be used in culture or in vivo (for nonhuman studies) for functional assays blocking, neutralizing, activation or depletion where the presence of azide may damage cells or exogenous endotoxin may signal or activate cells.
- Shipping Conditions:
- Blue Ice