E-AB-F11140
Purified Anti-Mouse CD183/CXCR3 Antibody[CXCR3-173], Functional Grade
Size
£80.10
Was £89.00
- SKU:
- E-AB-F11140
- Additional Names:
- C-X-C chemokine receptor type 3,CD183/CXCR3,CXC-R3,CXCR-3,Cxcr3,IP-10 receptor,Interferon-inducible protein 10 receptor
- Application:
- Flow Cytometry, Neutralisation
- Concentration:
- >= 1 mg/ml
- Storage Conditions:
- 2-8[o]C Avoid freeze/thaw cycles., -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Host:
- Hamster
- Reactivities:
- Mouse
- Buffer:
- Sterile PBS, pH 7.2. < 1.0 EU per mg of the antibody as determined by the LAL method.
- Clone:
- CXCR3-173
- Uniprot:
- O88410
- Synonyms:
- C-X-C chemokine receptor type 3;Cd183;Cmka;Cmkar3;Cxcr;interferon-inducible protein 10 receptor;IP-10 receptor
- Extra Details:
- CD183/CXCR3, also known as CXCR3, is a member of the C-X-C chemokine family, characterized by a pair of cysteine residues separated by a single amino acid. CXCR3 is a 38 kD seven pass transmembrane receptor coupled to G-protein. It mediates Ca2+ mobilization and chemotaxis in response to C-X-C chemokines, such as IP10 (CXCL10), MIG (CXCL9), I-TAC (CXCL11) and PF4 (CXCL4). CXCR3 is expressed primarily on activiated T lymphocytes, NK cells, and some epithelial cells and endothelial cells. It is not expressed on B cells, monocytes or granulocytes. None (Azide-Free,Low Endotoxin) are perfectly suited to be used in culture or in vivo (for nonhuman studies) for functional assays blocking, neutralizing, activation or depletion where the presence of azide may damage cells or exogenous endotoxin may signal or activate cells.
- Shipping Conditions:
- Blue Ice