E-AB-F11130
Purified Anti-Mouse CD18 Antibody[M18/2], Functional Grade
Size
£80.10
Was £89.00
- SKU:
- E-AB-F11130
- Additional Names:
- Integrin beta,ITGB,CD18,Cell surface adhesion glycoproteins LFA-1/CR3/p150+95 subunit beta,Complement receptor C3 subunit beta,Integrin beta-2,Itgb2,&,beta-2 integrin-n
- Application:
- Flow Cytometry
- Concentration:
- >= 1 mg/ml
- Purification:
- protein a/g purified
- Storage Conditions:
- 2-8[o]C Avoid freeze/thaw cycles., -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Host:
- Rat
- Reactivities:
- Mouse
- Buffer:
- Sterile PBS, pH 7.2. < 1.0 EU per mg of the antibody as determined by the LAL method.
- Immunogen:
- Recombinant Mouse CD18 protein
- Clone:
- M18/2
- Uniprot:
- P11835
- Synonyms:
- 2E6;AI528527;Cd18;cell surface adhesion glycoproteins LFA-1/CR3/p150,95 subunit beta;complement receptor C3 subunit beta;integrin beta-2;LAD;LCAMB;Lfa1;lymphocyte function associated antigen 1;Mac-1 beta;macrophage antigen-1 beta;MF17
- Extra Details:
- CD18 is a 95 kD protein, also known as integrin B Beta2 subunit. It is expressed on all leukocytes. CD18, in association with integrin A Alpha chain CD11a, CD11b, and CD11c forms LFA-1, Mac-1, and A AlphaXB Beta2, respectively, and plays an important role in leukocytes adhesion. The CD18 integrin complexes bind ICAM-1 (CD54), ICAM-2 (CD102), ICAM-3 (CD50), iC3b, and fibrinogen. The M18/2 antibody is able to block tumor cell metastasis and enhance cell adhesion. None (Azide-Free,Low Endotoxin) are perfectly suited to be used in culture or in vivo (for nonhuman studies) for functional assays blocking, neutralizing, activation or depletion where the presence of azide may damage cells or exogenous endotoxin may signal or activate cells.
- Shipping Conditions:
- Blue Ice