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  2. Monoclonal

E-AB-F11000

Purified Anti-Human/Mouse CD44 Antibody[IM7], Functional Grade

Size

£80.10

Was £89.00

SKU:
E-AB-F11000
Additional Names:
MDU2, MDU3, MIC4,CD44,CD44 antigen,CDw44,Epican,LHR,PGP-1,PGP-I,Phagocytic glycoprotein 1,Phagocytic glycoprotein I
Application:
Flow Cytometry
Concentration:
>= 1 mg/ml
Purification:
protein a/g purified
Storage Conditions:
2-8[o]C Avoid freeze/thaw cycles., -20[o]C Avoid freeze/thaw cycles.
Supplier:
Elabscience
Host:
Rat
Reactivities:
Human, Mouse
Buffer:
Sterile PBS, pH 7.2. < 1.0 EU per mg of the antibody as determined by the LAL method.
Immunogen:
Recombinant Human,Mouse CD44 protein
Clone:
IM7
Uniprot:
P15379, P16070
Synonyms:
AU023126;AW121933;AW146109;CD44 antigen;CDW44;cell surface glycoprotein CD44;chondroitin sulfate proteoglycan 8;CSPG8;ECMR-III;epican;extracellular matrix receptor III;GP90 lymphocyte homing/adhesion receptor;HCELL;hematopoietic cell E- and L-selectin ligand;heparan sulfate proteoglycan;HERM;HERMES;Hermes antigen;homing function and Indian blood group system;HUTCH-I;hyaluronate receptor;IN;Indian blood group antigen;LHR;Ly-2;Ly-24;lymphocyte antigen 24;MC56;MDU2;MDU3;MIC4;MTCTRI2_0792;Pgp;Pgp-1;PGP-I;Pgp1;phagocytic glycoprotein 1;phagocytic glycoprotein I;soluble CD44
Extra Details:
CD44 is a 80-95 kD glycoprotein also known as Hermes, Pgp1, H-CAM, or HUTCH. It is expressed on all leukocytes, endothelial cells, hepatocytes, and mesenchymal cells. As B and T cells become activated or progress to the memory stage, CD44 expression increases from low or mid levels to high levels. Thus, CD44 has been reported to be a valuable marker for memory cell subsets. High CD44 expression on Treg cells has been associated with potent suppressive function via high production of IL-10. CD44 is an adhesion molecule involved in leukocyte attachment to and rolling on endothelial cells, homing to peripheral lymphoid organs and to the sites of inflammation, and leukocyte aggregation. None (Azide-Free,Low Endotoxin) are perfectly suited to be used in culture or in vivo (for nonhuman studies) for functional assays blocking, neutralizing, activation or depletion where the presence of azide may damage cells or exogenous endotoxin may signal or activate cells.
Shipping Conditions:
Blue Ice