APC Anti-Rat CD8a Antibody[OX-8]

Size

£63.90

Was £71.00

SKU:: E-AB-F1098E
Additional Names:: CD8A,MAL,T-cell surface glycoprotein CD8 alpha chain,T-lymphocyte differentiation antigen T8/Leu-2
Application:: Flow Cytometry
Storage Conditions:: 2-8[o]C Do not freeze. Protect from light.
Supplier:: Elabscience
Host:: Mouse
Reactivities:: Rat
Buffer:: PBS
Immunogen:: CD8a
Clone:: OX-8
Uniprot:: P07725
Synonyms:: CD8 antigen 32 kDa chain;CD8 antigen, alpha-chain;OX-8 membrane antigen;T-cell surface glycoprotein CD8 alpha chain
Extra Details:: CD8a is a 32 kD glycoprotein also known as T8, Lyt2, Ly-2, and CD8A Alpha. CD8a is a member of the immunoglobulin superfamily expressed on most thymocytes, subset of mature T cells, most NK cells, macrophages, and some activated CD4+ T cells (not resting). CD8a forms heterodimers with the CD8B Beta chain (CD8b) on the surface of most thymocytes, while mature peripheral T lymphocytes express almost exclusively the CD8 A AlphaB Beta heterodimer. Intestinal intraepithelial lymphocytes express CD8a without CD8b. CD8 is an antigen co-receptor on T cells that interacts with MHC class I on antigen-presenting cells or epithelial cells. CD8 participates in T cell activation through its association with the T cell receptor complex and protein tyrosine kinase lck (p56lck).