E-AB-F10750
Purified Anti-Human CD32 Antibody[IV-3], Functional Grade
Size
£80.10
Was £89.00
- SKU:
- E-AB-F10750
- Additional Names:
- FCG,CDw,Fcgr,IGFR,FCGR2B,CD32,CD32B,FCG2,FCGR2,IGFR2,CDw32,Fc-gamma-RIIb,FcRII-b,Low affinity immunoglobulin gamma Fc region receptor II-b,IgG Fc receptor II-b,Fc-gamma RII-b,CD32 antigen,Fc fragment of IgG,Fc gamma receptor IIB,Fc gamma RII,Fc gamma RIIB,FCG2B,Fc-gamma RII,FCRII,FcG GammaRII,IgG Fc receptor II beta,low affinity II,low affinity IIb,Low affinity immunoglobulin gamma Fc region receptor II,Ly-17,Lym 1,Lymphocyte antigen 17,receptor,receptor (CD32),receptor for,receptor for (CD32)
- Application:
- Flow Cytometry
- Concentration:
- >= 1 mg/ml
- Purification:
- protein a/g purified
- Storage Conditions:
- 2-8[o]C Avoid freeze/thaw cycles., -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Host:
- Mouse
- Reactivities:
- Human
- Buffer:
- Sterile PBS, pH 7.2. < 1.0 EU per mg of the antibody as determined by the LAL method.
- Immunogen:
- Recombinant Human CD32 protein
- Clone:
- IV-3
- Uniprot:
- P31994
- Synonyms:
- CD32;CD32B;CDw32;Fc fragment of IgG, low affinity II, receptor for (CD32);Fc fragment of IgG, low affinity IIb, receptor (CD32);Fc fragment of IgG, low affinity IIb, receptor for (CD32);Fc gamma receptor IIb;Fc gamma RIIb;fc-gamma RII-b;Fc-gamma RII-c;fc-gamma-RIIb;Fc-gamma-RIIc;FCG2;FCGR2;FCGR2C;fcRII-b;FcRII-c;IGFR2;igG Fc receptor II-b;IgG Fc receptor II-c;low affinity immunoglobulin gamma Fc region receptor II-b;Low affinity immunoglobulin gamma Fc region receptor II-c
- Extra Details:
- CD32 is a 40 kD polymorphic transmembrane glycoprotein also known as FcG GammaRII and FCRII. It is an immunoglobulin superfamily member expressed on monocytes/macrophages, granulocytes, platelets and B cells. There are at least 6 isoforms of CD32 resulting from alternative mRNA splicing. CD32 mediates phagocytosis and oxidative burst in granulocytes, as well as platelet aggregation and immunomodulation. The extracellular domain of CD32 binds to polymeric and aggregated IgG and immune complexes, while the intracellular domain has been reported to associate with SHP-1 (B1 isoform). None (Azide-Free,Low Endotoxin) are perfectly suited to be used in culture or in vivo (for nonhuman studies) for functional assays blocking, neutralizing, activation or depletion where the presence of azide may damage cells or exogenous endotoxin may signal or activate cells.
- Shipping Conditions:
- Blue Ice