APC Anti-Human CD58 Antibody[TS2/9.1]

Size

£97.20

Was £108.00

SKU:: E-AB-F1068E
Additional Names:: Ag3,CD58,LFA3,Lymphocyte function-associated antigen 3,Surface glycoprotein LFA-3
Application:: Flow Cytometry
Storage Conditions:: 2-8[o]C Do not freeze. Protect from light.
Supplier:: Elabscience
Host:: Mouse
Reactivities:: Human
Buffer:: PBS
Immunogen:: CD58
Clone:: TS2/9.1
Uniprot:: P19256
Synonyms:: ag3;CD58 antigen, (lymphocyte function-associated antigen 3);LFA-3;LFA3;lymphocyte function-associated antigen 3;surface glycoprotein LFA-3
Extra Details:: CD58, also known as lymphocyte function-associated antigen 3 (LFA-3) is a 45-70 kD cell surface protein that is a member of the immunoglobulin superfamily. Alternative splicing of CD58 gives rise to transmembrane and glycosylphosphatidylinositol (GPI)-anchored forms on cell surface. CD58 is expressed on both hematopoietic and non-hematopoietic cells including B cells, T cells, monocytes, erythrocytes, endothelial cells, epithelial cells, and fibroblasts. High levels are observed on memory T cells and dendritic cells. CD58 expressed on antigen presenting cells and target cells enhances T cell recognition via the binding of it's cognate ligand, CD2, on the T cell surface.