E-AB-F10350
Purified Anti-Mouse CD120b/TNFR2 Antibody[TR75-54.7], Functional Grade
Size
£80.10
Was £89.00
- SKU:
- E-AB-F10350
- Additional Names:
- CD120b,TNF-R2,TNF-RII,TNFR-II,Tnfrsf1b,Tumor necrosis factor receptor 2,Tumor necrosis factor receptor superfamily member 1B,p75,p80 TNF-alpha receptor
- Application:
- Flow Cytometry, Neutralisation
- Concentration:
- >= 1 mg/ml
- Storage Conditions:
- 2-8[o]C Avoid freeze/thaw cycles., -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Host:
- Hamster
- Reactivities:
- Mouse
- Buffer:
- Sterile PBS, pH 7.2. < 1.0 EU per mg of the antibody as determined by the LAL method.
- Clone:
- TR75-54.7
- Uniprot:
- P25119
- Synonyms:
- CD120b;p7;p75;p75 TNFR;p80 TNF-alpha receptor;TN;Tnf;TNF receptor beta chain;TNF-;TNF-a;TNF-alphaR2;TNF-R;TNF-R-II;TNF-R2;TNF-R75;TNF-RII;TNFal;TNFalpha-R2;TNFBR;TNFR;Tnfr-1;TNFR-II;Tnfr2;TNFR80;TNFRII;tumor necrosis factor receptor 2;tumor necrosis factor receptor superfamily member 1B;tumor necrosis factor receptor type II
- Extra Details:
- CD120b is a 75 kD type I transmembrane protein, also known as Tumor Necrosis Factor Receptor Type II (TNFRII) or p75. It is expressed on a variety of cells at low levels, the expression is upregulated upon activation. This receptor binds both TNF-A Alpha and LT-A Alpha (also known as TNF-B Beta). In association with TRAF1 and TRAF2, the receptor crosslinking induced by TNF-A Alpha or LT-A Alpha trimers is critical for signal transduction, leading to apoptosis, NF-kB activation, increased expression of proinflammatory genes, tumor necrosis, and cell differentiation depending on cell type and differentiation state. None (Azide-Free,Low Endotoxin) are perfectly suited to be used in culture or in vivo (for nonhuman studies) for functional assays blocking, neutralizing, activation or depletion where the presence of azide may damage cells or exogenous endotoxin may signal or activate cells.
- Shipping Conditions:
- Blue Ice