APC Anti-Mouse CD40 Antibody[FGK4.5/FGK45]

Size

£90.90

Was £101.00

SKU:: E-AB-F1028E
Additional Names:: B-cell surface antigen CD40,Bp50,CD40,CD40L receptor,Cd40,Tnfrsf5,Tumor necrosis factor receptor superfamily member 5
Application:: Flow Cytometry
Storage Conditions:: 2-8[o]C Do not freeze. Protect from light.
Supplier:: Elabscience
Host:: Rat
Reactivities:: Mouse
Buffer:: PBS
Immunogen:: CD40
Clone:: FGK4.5/FGK45
Uniprot:: P27512
Synonyms:: AI326936;B-cell surface antigen CD40;Bp5;Bp50;CD40L receptor;GP39;HIGM1;IGM;IMD3;p5;p50;T-BAM;T-cell differentiation antigen;Tnfr;Tnfrsf5;TRAP;tumor necrosis factor receptor superfamily member 5
Extra Details:: CD40 is a 48 kD type I transmembrane glycoprotein also known as Bp50. It is a member of the tumor necrosis factor receptor (TNFR) superfamily and is expressed on B cells, basal epithelial cells, macrophages, follicular dendritic cells, endothelial cells, and a subset of CD34+ hematopoietic progenitors. CD40 regulates B cell development/maturation, Ig isotype switching and, in combination with other signals such as IL-4, protects B cells from surface Ig-induced apoptosis and promotes proliferation. Interaction of CD40 with its ligand CD154 (gp39), which is expressed on activated T cells, is important in costimulation and immune regulation.