Biotin Anti-Mouse CD209b Antibody[22D1]

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£82.80

Was £92.00

SKU:: E-AB-F1022B
Additional Names:: CD209,CD209 antigen-like protein B,Cd209b,DC-SIGN-related protein 1,DC-SIGNR1,OtB7
Application:: Flow Cytometry
Concentration:: 0.5 mg/ml
Storage Conditions:: 2-8[o]C Do not freeze.
Supplier:: Elabscience
Host:: Hamster
Reactivities:: Mouse
Buffer:: PBS
Immunogen:: CD209b
Clone:: 22D1
Uniprot:: Q8CJ91
Synonyms:: 1810030I22Rik;CD209 antigen-like protein B;DC-SIGN-related protein 1;DC-SIGNR1;mSI;mSIGNR1;OtB7;SI;SIGNR1
Extra Details:: CD209B, also known as SIGN-R1, is a mouse C-type lectin receptor predominantly expressed on macrophages in the spleen marginal zone and lymph nodes medulla. CD209B is a mouse homolog of human CD209/DC-SIGN and is involved in innate immune response. CD209B mediates the recognition and uptake of pathogen products, such as lipopolysaccharides (LPS), pneumococcal polysaccharides, and dextrans. CD209B has been demonstrated to facilitate the clearance of encapsulated pneumococcus by directly binding to C1q and activating complement through an immunoglobulin independent pathway.