E-AB-F10220
Purified Anti-Mouse CD209b Antibody[22D1], Functional Grade
Size
£80.10
Was £89.00
- SKU:
- E-AB-F10220
- Additional Names:
- OtB,DC-SIGN-related protein,DC-SIGNR,CD209,CD209 antigen-like protein B,DC-SIGNR1,DC-SIGN-related protein 1,OtB7,Cd209b
- Application:
- Flow Cytometry
- Concentration:
- >= 1 mg/ml
- Purification:
- protein a/g purified
- Storage Conditions:
- 2-8[o]C Avoid freeze/thaw cycles., -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Host:
- Hamster
- Reactivities:
- Mouse
- Buffer:
- Sterile PBS, pH 7.2. < 1.0 EU per mg of the antibody as determined by the LAL method.
- Immunogen:
- Recombinant Mouse CD209b protein
- Clone:
- 22D1
- Uniprot:
- Q8CJ91
- Synonyms:
- 1810030I22Rik;CD209 antigen-like protein B;DC-SIGN-related protein 1;DC-SIGNR1;mSI;mSIGNR1;OtB7;SI;SIGNR1
- Extra Details:
- CD209B, also known as SIGN-R1, is a mouse C-type lectin receptor predominantly expressed on macrophages in the spleen marginal zone and lymph nodes medulla. CD209B is a mouse homolog of human CD209/DC-SIGN and is involved in innate immune response. CD209B mediates the recognition and uptake of pathogen products, such as lipopolysaccharides (LPS), pneumococcal polysaccharides, and dextrans. CD209B has been demonstrated to facilitate the clearance of encapsulated pneumococcus by directly binding to C1q and activating complement through an immunoglobulin independent pathway. None (Azide-Free,Low Endotoxin) are perfectly suited to be used in culture or in vivo (for nonhuman studies) for functional assays blocking, neutralizing, activation or depletion where the presence of azide may damage cells or exogenous endotoxin may signal or activate cells.
- Shipping Conditions:
- Blue Ice