Biotin Anti-Mouse CD132 Antibody[3E12]

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£72.90

Was £81.00

SKU:: E-AB-F1015B
Additional Names:: CD132,Cytokine receptor common subunit gamma,IL-2 receptor subunit gamma,IL-2R subunit gamma,IL-2RG,Il2rg,Interleukin-2 receptor subunit gamma,gammaC,p64
Application:: Flow Cytometry
Concentration:: 0.5 mg/ml
Storage Conditions:: 2-8[o]C Do not freeze.
Supplier:: Elabscience
Host:: Rat
Reactivities:: Mouse
Buffer:: PBS
Immunogen:: CD132
Clone:: 3E12
Uniprot:: P34902
Synonyms:: [g]c;CD132;common gamma chain;cytokine receptor common subunit gamma;gamm;gamma C receptor;gamma(;gamma(c);gammaC;gc;IL-2 receptor subunit gamma;IL-2R subunit gamma;interleukin-2 receptor subunit gamma;p64
Extra Details:: CD132 is a 64-70 kD type I transmembrane glycoprotein of the Ig superfamily, and is also known as common G Gamma chain (G Gammac) or IL-2 receptor G Gamma subunit. It is expressed broadly on T- and B-lymphocytes, NK cells, monocytes, and granulocytes. CD132 is an essential component of cytokine receptors for IL-2, IL-4, IL-7, IL-9, IL-15, and IL-21. Ligand binding induces tyrosine phosphorylation and initiates signaling through a JAK/STAT pathway. CD132 mutation results in X-linked severe combined immune deficiency (XSCID).