E-AB-F10150
Purified Anti-Mouse CD132 Antibody[3E12], Functional Grade
Size
£80.10
Was £89.00
- SKU:
- E-AB-F10150
- Additional Names:
- CD132,Cytokine receptor common subunit gamma,IL-2 receptor subunit gamma,IL-2R subunit gamma,IL-2RG,Il2rg,Interleukin-2 receptor subunit gamma,gammaC,p64
- Application:
- Flow Cytometry
- Concentration:
- >= 1 mg/ml
- Storage Conditions:
- 2-8[o]C Avoid freeze/thaw cycles., -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Host:
- Rat
- Reactivities:
- Mouse
- Buffer:
- Sterile PBS, pH 7.2. < 1.0 EU per mg of the antibody as determined by the LAL method.
- Clone:
- 3E12
- Uniprot:
- P34902
- Synonyms:
- [g]c;CD132;common gamma chain;cytokine receptor common subunit gamma;gamm;gamma C receptor;gamma(;gamma(c);gammaC;gc;IL-2 receptor subunit gamma;IL-2R subunit gamma;interleukin-2 receptor subunit gamma;p64
- Extra Details:
- CD132 is a 64-70 kD type I transmembrane glycoprotein of the Ig superfamily, and is also known as common G Gamma chain (G Gammac) or IL-2 receptor G Gamma subunit. It is expressed broadly on T- and B-lymphocytes, NK cells, monocytes, and granulocytes. CD132 is an essential component of cytokine receptors for IL-2, IL-4, IL-7, IL-9, IL-15, and IL-21. Ligand binding induces tyrosine phosphorylation and initiates signaling through a JAK/STAT pathway. CD132 mutation results in X-linked severe combined immune deficiency (XSCID). None (Azide-Free,Low Endotoxin) are perfectly suited to be used in culture or in vivo (for nonhuman studies) for functional assays blocking, neutralizing, activation or depletion where the presence of azide may damage cells or exogenous endotoxin may signal or activate cells.
- Shipping Conditions:
- Blue Ice