Purified Anti-Mouse CD62L Antibody[MEL-14], Functional Grade

Size

£80.10

Was £89.00

SKU:: E-AB-F10110
Additional Names:: CD62L,CD62 antigen-like family member L,L-selectin,LAM-1,LECAM1,Lnhr,Ly-22,Ly22,Lymph node homing receptor,Sell
Application:: Flow Cytometry, Neutralisation
Concentration:: >= 1 mg/ml
Storage Conditions:: 2-8[o]C Avoid freeze/thaw cycles., -20[o]C Avoid freeze/thaw cycles.
Supplier:: Elabscience
Host:: Rat
Reactivities:: Mouse
Buffer:: Sterile PBS, pH 7.2. < 1.0 EU per mg of the antibody as determined by the LAL method.
Clone:: MEL-14
Uniprot:: P18337
Synonyms:: AI528707;CD62;CD62 antigen-like family member L;CD62L;L;L-sel;L-selectin;LAM-1;LECAM;LECAM-1;LECAM1;leukocyte adhesion molecule 1;leukocyte-endothelial cell adhesion molecule 1;Lnhr;Ly-2;Ly-22;Ly-m2;Ly-m22;Lya;Lyam;Lyam-1;Lyam1;lymph node homing receptor;lymphocyte antigen 22;lymphocyte surface MEL-14 antigen
Extra Details:: CD62L is a 74-95 kD glycoprotein also known as L-selectin, LECAM-1, Ly-22, LAM-1, and MEL-14. It is a member of the selectin family and is expressed on the majority of B and naive T cells, a subset of memory T cells, monocytes, granulocytes, most thymocytes, and a subset of NK cells. CD62L is important in lymphocyte homing to high endothelial venules (HEV) in peripheral lymph nodes and leukocyte 'rolling' on activated endothelium. CD62L also contributes to neutrophil emigration at inflammatory sites. CD62L is rapidly shed from lymphocytes and neutrophils upon cellular activation and the expression levels of CD62L (in conjunction with other markers) have been used to distinguish naive, effector, and memory T cells. CD62L has been reported to interact with CD34, GlyCAM-1, and MAdCAM-1. None (Azide-Free,Low Endotoxin) are perfectly suited to be used in culture or in vivo (for nonhuman studies) for functional assays blocking, neutralizing, activation or depletion where the presence of azide may damage cells or exogenous endotoxin may signal or activate cells.

Shipping Conditions:: Blue Ice