PE Anti-Mouse CD86 Antibody[GL-1]

Size

£84.60

Was £94.00

SKU:: E-AB-F0994D
Additional Names:: Activation B7-2 antigen,Cd86,ETC-1,Early T-cell costimulatory molecule 1,T-lymphocyte activation antigen CD86
Application:: Flow Cytometry
Storage Conditions:: 2-8[o]C Do not freeze. Protect from light.
Supplier:: Elabscience
Host:: Rat
Reactivities:: Mouse
Buffer:: PBS
Immunogen:: CD86
Clone:: GL-1
Uniprot:: P42082
Synonyms:: activation B7-2 antigen;B7;B7-2;B7.2;B70;Cd28l;Cd28l2;CLS1;early T cell costimulatory molecule-1;Early T-cell costimulatory molecule 1;ETC-1;Ly-5;Ly-58;Ly5;Ly58;MB7;MB7-2;T-lymphocyte activation antigen CD86;TS/A-2
Extra Details:: CD86 is an 80 kD immunoglobulin superfamily member also known as B7-2, B70, and Ly-58. CD86 is expressed on activated B and T cells, macrophages, dendritic cells, and astrocytes. CD86, along with CD80, is a ligand of CD28 and CD152 (CTLA-4). CD86 is expressed earlier in the immune response than CD80. CD86 has also been shown to be involved in immunoglobulin class-switching and triggering of NK cell-mediated cytotoxicity. CD86 binds to CD28 to transduce co-stimulatory signals for T cell activation, proliferation, and cytokine production. CD86 can also bind to CD152, also known as CTLA-4, to deliver an inhibitory signal to T cells.