Purified Anti-Mouse CD161/NK1.1 Antibody[PK136], Functional Grade

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£80.10

Was £89.00

SKU:: E-AB-F09870
Additional Names:: CD161 antigen-like family member C,CD161/NK1.1,CD161c,Killer cell lectin-like receptor subfamily B member 1C,Klrb1c,Ly-55c,NKR-P1 40,NKR-P1.9,NKR-P1C
Application:: Flow Cytometry
Concentration:: >= 1 mg/ml
Purification:: protein a/g purified
Storage Conditions:: 2-8[o]C Avoid freeze/thaw cycles., -20[o]C Avoid freeze/thaw cycles.
Supplier:: Elabscience
Host:: Mouse
Reactivities:: Mouse
Buffer:: Sterile PBS, pH 7.2. < 1.0 EU per mg of the antibody as determined by the LAL method.
Immunogen:: Recombinant Mouse NK1.1 protein
Clone:: PK136
Uniprot:: P27812, P27814, Q99JB4
Synonyms:: AI462337;CD161;CD161 antigen-like family member B;CD161 antigen-like family member C;inhibitory receptor NKR-P1B;killer cell lectin-like receptor subfamily A member 1C;killer cell lectin-like receptor subfamily B member 1B allele A;killer cell lectin-like receptor subfamily B member 1B allele B;killer cell lectin-like receptor subfamily B member 1C;killer cell lectin-like receptor subfamily B member 1D;Klrb;Klrb1b;Klrb1d;Ly-5;ly-55b;ly-55c;ly-55d;Ly-59;Ly5;Ly55;Ly55b;Ly55c;Ly55d;Ly59;lymphocyte antigen 55 complex, locus B;lymphocyte antigen 55 complex, locus C;lymphocyte antigen 55 complex, locus D;lymphocyte antigen 55b;lymphocyte antigen 55c;lymphocyte antigen 55d;lymphocyte antigen 59;natural killer cell receptor protein NKR-P1B;natural killer cell receptor protein NKR-P1C;natural killer cell receptor-P1;natural killer cell surface protein NKR-P1B allele B6;natural killer cell surface protein NKR-P1B allele SJL/BALB;natural killer cell surface protein P1-40;natural killer cell-associated antigen 1;Nk;NK-;Nk-1;NK-1.;Nk-1.2;NK-RP1;Nk1;Nk1.;NK1.1;Nk1.2;NKR;NKR-;NKR-P1 34;NKR-P1 40;NKR-P1.9;NKR-P1B;NKR-P1C;NKR-P1D;Nkrp;NKRP1;Nkrp1-b;NKRP140;Nkrp1b;Nkrp1c;Nkrp1d
Extra Details:: NK-1.1 surface antigen, also known as CD161b/CD161c and Ly-55, is encoded by the NKR-P1B/NKR-P1C gene. It is expressed on NK cells and NK-T cells in some mouse strains, including C57BL/6, FVB/N, and NZB, but not AKR, BALB/c, CBA/J, C3H, DBA/1, DBA/2, NOD, SJL, and 129. Expression of NKR-P1C antigen has been correlated with lysis of tumor cells in vitro and rejection of bone marrow allografts in vivo. NK-1.1 has also been shown to play a role in NK cell activation, IFN-G Gamma production, and cytotoxic granule release. NK-1.1 and DX5 are commonly used as mouse NK cell markers. None (Azide-Free,Low Endotoxin) are perfectly suited to be used in culture or in vivo (for nonhuman studies) for functional assays blocking, neutralizing, activation or depletion where the presence of azide may damage cells or exogenous endotoxin may signal or activate cells.

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