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E-AB-93389

ASGR2 Polyclonal Antibody

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£195.30

Was £217.00

SKU:
E-AB-93389
Additional Names:
ASGP-R2,ASGPR2,ASGR2,CLEC4H2,HBXBP,HL-2
Application:
WB
Concentration:
1 mg/ml
Purification:
Affinity Purified
Storage Conditions:
-20[o]C Avoid freeze/thaw cycles.
Supplier:
Elabscience
Host:
Rabbit
Reactivities:
Human
Buffer:
Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
Immunogen:
Recombinant fusion protein of human ASGR2
Uniprot:
P07307
Synonyms:
ASGP-R2;ASGPR2;asialoglycoprotein receptor 2;C-type lectin domain family 4 member H2;CLEC4H2;HBxAg-binding protein;HBXBP;hepatic lectin H2;HL-2
Extra Details:
This gene encodes a subunit of the asialoglycoprotein receptor. This receptor is a transmembrane protein that plays a critical role in serum glycoprotein homeostasis by mediating the endocytosis and lysosomal degradation of glycoproteins with exposed terminal galactose or N-acetylgalactosamine residues. The asialoglycoprotein receptor may facilitate hepatic infection by multiple viruses including hepatitis B, and is also a target for liver-specific drug delivery. The asialoglycoprotein receptor is a hetero-oligomeric protein composed of major and minor subunits, which are encoded by different genes. The protein encoded by this gene is the less abundant minor subunit. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
Shipping Conditions:
Blue Ice