E-AB-93371
PRG2 Polyclonal Antibody
Size
£195.30
Was £217.00
- SKU:
- E-AB-93371
- Additional Names:
- BMPG,MBP,MBP1,PRG2,proMBP
- Application:
- IHC, WB, IF
- Concentration:
- 1 mg/ml
- Purification:
- Affinity Purified
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Host:
- Rabbit
- Reactivities:
- Human, Mouse, Rat
- Buffer:
- Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
- Immunogen:
- A synthetic peptide of human PRG2
- Uniprot:
- P13727
- Synonyms:
- BMPG;bone marrow proteoglycan;eosinophil granule major basic protein;eosinophil major basic protein;MBP;MBP1;natural killer cell activator;proMBP;Proteoglycan 2;proteoglycan 2 preproprotein;proteoglycan 2, bone marrow (natural killer cell activator, eosinophil granule major basic protein)
- Extra Details:
- The protein encoded by this gene is the predominant constituent of the crystalline core of the eosinophil granule. High levels of the proform of this protein are also present in placenta and pregnancy serum, where it exists as a complex with several other proteins including pregnancy-associated plasma protein A (PAPPA), angiotensinogen (AGT), and C3dg. This protein may be involved in antiparasitic defense mechanisms as a cytotoxin and helminthotoxin, and in immune hypersensitivity reactions. The encoded protein contains a peptide that displays potent antimicrobial activity against Gram-positive bacteria, Gram-negative bacteria, and fungi. It is directly implicated in epithelial cell damage, exfoliation, and bronchospasm in allergic diseases. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
- Shipping Conditions:
- Blue Ice