E-AB-93268
CD152/CTLA-4 Polyclonal Antibody
Size
£195.30
Was £217.00
- SKU:
- E-AB-93268
- Additional Names:
- ALPS5,CD,CD152,CELIAC3,CTLA-4,CTLA4,GRD4,GSE,IDDM12
- Application:
- IHC, WB
- Concentration:
- 1 mg/ml
- Purification:
- Affinity Purified
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Host:
- Rabbit
- Reactivities:
- Human, Mouse, Rat
- Buffer:
- Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
- Immunogen:
- Recombinant fusion protein of human CD152/CTLA-4
- Uniprot:
- P16410
- Synonyms:
- ALPS5;CD;CD152;celiac disease 3;CELIAC3;CTLA-4;cytotoxic T lymphocyte associated antigen 4 short spliced form;cytotoxic T-lymphocyte protein 4;Cytotoxic T-lymphocyte-associated antigen 4;cytotoxic T-lymphocyte-associated serine esterase-4;GRD4;GSE;IDDM12;insulin-dependent diabetes mellitus 12;ligand and transmembrane spliced cytotoxic T lymphocyte associated antigen 4
- Extra Details:
- This gene is a member of the immunoglobulin superfamily and encodes a protein which transmits an inhibitory signal to T cells. The protein contains a V domain, a transmembrane domain, and a cytoplasmic tail. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. The membrane-bound isoform functions as a homodimer interconnected by a disulfide bond, while the soluble isoform functions as a monomer. Mutations in this gene have been associated with insulin-dependent diabetes mellitus, Graves disease, Hashimoto thyroiditis, celiac disease, systemic lupus erythematosus, thyroid-associated orbitopathy, and other autoimmune diseases.
- Shipping Conditions:
- Blue Ice