E-AB-93262
IL18 Polyclonal Antibody
Size
£211.50
Was £235.00
- SKU:
- E-AB-93262
- Additional Names:
- Interleukin,IL-1F,Ig,Il-Igif,Il-18,IFN-gamma-inducing factor,Il,IL-1 gamma,IL-1F4,IL-1g,Interferon gamma-inducing factor,Interferon-gamma-inducing factor,Interleukin-1 gamma,Interleukin-18,Igif,Il18,Igif,Il-,Il-18
- Application:
- IHC, WB
- Concentration:
- 1 mg/ml
- Purification:
- Affinity Purified
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Host:
- Rabbit
- Reactivities:
- Human, Mouse, Rat
- Buffer:
- Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
- Immunogen:
- Recombinant fusion protein of mouse IL18
- Uniprot:
- P70380
- Synonyms:
- IFN-gamma-inducing factor;Ig;Igif;Il-;IL-1 gamma;Il-18;interferon gamma-inducing factor;interleukin-1 gamma;interleukin-18
- Extra Details:
- Interleukin-18 (L-18) is a cytokine that belongs to the IL-1 superfamily and is produced by macrophages and other cells. IL-18 works by binding to the interleukin-18 receptor, and together with IL-12 it induces cell-mediated immunity following infection with microbial products like lipopolysaccharide (LPS). After stimulation with IL-18, natural killer (NK) cells and certain T cells release another important cytokine called interferon-G Gamma (IFN-G Gamma) or type II interferon that plays an important role in activating the macrophages or other cells. The combination of this cytokine and IL12 has been shown to inhibit IL-4 dependent IgE and IgG1 production, and enhance IgG2a production in B cells. IL-18 binding protein (IL18BP) can specifically interact with this cytokine, and thus negatively regulate its biological activity.
- Shipping Conditions:
- Blue Ice