E-AB-93254
FADD Polyclonal Antibody
Size
£195.30
Was £217.00
- SKU:
- E-AB-93254
- Additional Names:
- Mort1/FADD,Mort1/F
- Application:
- WB, IF, IP
- Concentration:
- 1 mg/ml
- Purification:
- Affinity Purified
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Host:
- Rabbit
- Reactivities:
- Human, Mouse, Rat
- Buffer:
- Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
- Immunogen:
- Recombinant fusion protein of mouse FADD
- Uniprot:
- Q61160
- Synonyms:
- FAS-associated death domain protein;FAS-associating death domain-containing protein;Fas-associating protein with death domain;mediator of receptor induced toxicity;Mort1/F;Mort1/FADD;protein FADD
- Extra Details:
- Apoptotic adaptor molecule that recruits caspase-8 or caspase-10 to the activated Fas (CD95 or TNFR-1 receptors. The resulting aggregate called the death-inducing signaling complex (DISC performs caspase-8 proteolytic activation. Active caspase-8 initiates the subsequent cascade of caspases mediating apoptosis. Involved in interferon-mediated antiviral immune response, playing a role in the positive regulation of interferon signaling.
- Shipping Conditions:
- Blue Ice