PTH1R Polyclonal Antibody

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£195.30

Was £217.00

SKU:: E-AB-93210
Additional Names:: PFE,PTH1R,PTHR,PTHR1
Application:: IHC, WB
Concentration:: 1 mg/ml
Purification:: Affinity Purified
Storage Conditions:: -20[o]C Avoid freeze/thaw cycles.
Supplier:: Elabscience
Host:: Rabbit
Reactivities:: Human, Mouse, Rat
Buffer:: Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
Immunogen:: Recombinant fusion protein of human PTH1R
Uniprot:: Q03431
Synonyms:: EKNS;Parathyroid hormone 1 receptor;parathyroid hormone receptor 1;parathyroid hormone/parathyroid hormone-related peptide receptor;parathyroid hormone/parathyroid hormone-related protein receptor;PFE;PTH/PTHr receptor;PTH/PTHrP type I receptor;PTH1 receptor;PTHR;PTHR1;seven transmembrane helix receptor
Extra Details:: The protein encoded by this gene is a member of the G-protein coupled receptor family 2. This protein is a receptor for parathyroid hormone (PTH) and for parathyroid hormone-like hormone (PTHLH). The activity of this receptor is mediated by G proteins which activate adenylyl cyclase and also a phosphatidylinositol-calcium second messenger system. Defects in this receptor are known to be the cause of Jansen's metaphyseal chondrodysplasia (JMC), chondrodysplasia Blomstrand type (BOCD), as well as enchodromatosis. Two transcript variants encoding the same protein have been found for this gene.