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E-AB-93139

ETV6 Polyclonal Antibody

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£195.30

Was £217.00

SKU:
E-AB-93139
Additional Names:
ETV6,TEL,TEL/ABL,THC5
Application:
WB
Concentration:
1 mg/ml
Purification:
Affinity Purified
Storage Conditions:
-20[o]C Avoid freeze/thaw cycles.
Supplier:
Elabscience
Host:
Rabbit
Reactivities:
Human, Mouse, Rat
Buffer:
Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
Immunogen:
Recombinant fusion protein of human ETV6
Uniprot:
P41212
Synonyms:
ETS translocation variant 6;ETS variant 6;ets variant gene 6 (TEL oncogene);ETS-related protein Tel1;TEL;TEL/ABL;TEL1 oncogene;THC5;transcription factor ETV6
Extra Details:
This gene encodes an ETS family transcription factor. The product of this gene contains two functional domains: a N-terminal pointed (PNT) domain that is involved in protein-protein interactions with itself and other proteins, and a C-terminal DNA-binding domain. Gene knockout studies in mice suggest that it is required for hematopoiesis and maintenance of the developing vascular network. This gene is known to be involved in a large number of chromosomal rearrangements associated with leukemia and congenital fibrosarcoma.
Shipping Conditions:
Blue Ice