E-AB-93137
NLRP6 Polyclonal Antibody
Size
£195.30
Was £217.00
- SKU:
- E-AB-93137
- Additional Names:
- AVR,CLR11.4,NALP6,NAVR,NAVR/AVR,NLRP6,PAN3,PYPAF5
- Application:
- WB
- Concentration:
- 1 mg/ml
- Purification:
- Affinity Purified
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Host:
- Rabbit
- Reactivities:
- Human, Mouse, Rat
- Buffer:
- Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
- Immunogen:
- A synthetic peptide of human NLRP6
- Uniprot:
- P59044
- Synonyms:
- angiotensin II/vasopressin receptor;AVR;CLR11.4;NACHT, leucine rich repeat and PYD containing 6;NACHT, LRR and PYD domains-containing protein 6;NALP6;NAVR;NAVR/AVR;nucleotide-binding oligomerization domain, leucine rich repeat and pyrin domain containing 6;PAN3;PYPAF5;PYRIN-containing APAF1-like protein 5
- Extra Details:
- The protein encoded by this gene binds arginine-vasopressin and may be involved in the arginine-vasopressin-mediated regulation of renal salt-water balance. The encoded protein also mediates inflammatory responses in the colon to allow recovery from intestinal epithelial damage and protects against tumorigenesis and the development of colitis. Finally, this protein can increase activation of NF-kappa-B, activation of CASP1 through interaction with ASC, and cAMP accumulation. Two transcript variants encoding different isoforms have been found for this gene.
- Shipping Conditions:
- Blue Ice