E-AB-93071
TAK1 Polyclonal Antibody
Size
£195.30
Was £217.00
- SKU:
- E-AB-93071
- Additional Names:
- CSCF,FMD2,MAP3K7,MEKK7,TAK1,TGF1a
- Application:
- IHC, WB, IF
- Concentration:
- 1 mg/ml
- Purification:
- Affinity Purified
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Host:
- Rabbit
- Reactivities:
- Human, Mouse, Rat
- Buffer:
- Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
- Immunogen:
- Recombinant fusion protein of human TAK1
- Uniprot:
- O43318
- Synonyms:
- CSCF;FMD2;MEKK7;mitogen-activated protein kinase kinase kinase 7;TAK1;TGF-beta activated kinase 1;TGF1a;transforming growth factor-beta-activated kinase 1
- Extra Details:
- The protein encoded by this gene is a member of the serine/threonine protein kinase family. This kinase mediates the signaling transduction induced by TGF beta and morphogenetic protein (BMP), and controls a variety of cell functions including transcription regulation and apoptosis. In response to IL-1, this protein forms a kinase complex including TRAF6, MAP3K7P1/TAB1 and MAP3K7P2/TAB2, this complex is required for the activation of nuclear factor kappa B. This kinase can also activate MAPK8/JNK, MAP2K4/MKK4, and thus plays a role in the cell response to environmental stresses. Four alternatively spliced transcript variants encoding distinct isoforms have been reported.
- Shipping Conditions:
- Blue Ice