E-AB-93002
RASA4 Polyclonal Antibody
Size
£195.30
Was £217.00
- SKU:
- E-AB-93002
- Additional Names:
- CAPRI,GAPL,RASA4
- Application:
- WB
- Concentration:
- 1 mg/ml
- Purification:
- Affinity Purified
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Host:
- Rabbit
- Reactivities:
- Human, Mouse, Rat
- Buffer:
- Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
- Immunogen:
- Recombinant fusion protein of human RASA4
- Uniprot:
- O43374
- Synonyms:
- Ca2+-promoted Ras inactivator;calcium-promoted Ras inactivator;CAPRI;GAPL;ras GTPase-activating protein 4;Ras p21 protein activator 4;rasGAP-activating-like protein 2
- Extra Details:
- This gene encodes a member of the GAP1 family of GTPase-activating proteins that suppresses the Ras/mitogen-activated protein kinase pathway in response to Ca(2+). Stimuli that increase intracellular Ca(2+) levels result in the translocation of this protein to the plasma membrane, where it activates Ras GTPase activity. Consequently, Ras is converted from the active GTP-bound state to the inactive GDP-bound state and no longer activates downstream pathways that regulate gene expression, cell growth, and differentiation. Multiple transcript variants encoding different isoforms have been found for this gene.
- Shipping Conditions:
- Blue Ice