E-AB-92999
UBTF Polyclonal Antibody
Size
£195.30
Was £217.00
- SKU:
- E-AB-92999
- Additional Names:
- NOR-90,UBF,UBF-1,UBF1,UBF2,UBTF
- Application:
- WB
- Concentration:
- 1 mg/ml
- Purification:
- Affinity Purified
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Host:
- Rabbit
- Reactivities:
- Human, Mouse, Rat
- Buffer:
- Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
- Immunogen:
- Recombinant fusion protein of human UBTF
- Uniprot:
- P17480
- Synonyms:
- 90-kDa nucleolus organizer region autoantigen;autoantigen NOR-90;CONDBA;NOR-90;nucleolar transcription factor 1;UBF;UBF-1;UBF1;UBF2;upstream binding transcription factor, RNA polymerase I;Upstream-binding factor 1
- Extra Details:
- This gene encodes a member of the HMG-box DNA-binding protein family. The encoded protein plays a critical role in ribosomal RNA transcription as a key component of the pre-initiation complex, mediating the recruitment of RNA polymerase I to rDNA promoter regions. The encoded protein may also play important roles in chromatin remodeling and pre-rRNA processing, and its activity is regulated by both phosphorylation and acetylation. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. Pseudogenes of this gene are located on the short arm of chromosomes 3, 11 and X and the long arm of chromosome 11.
- Shipping Conditions:
- Blue Ice