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E-AB-92994

ABCB4 Polyclonal Antibody

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£195.30

Was £217.00

SKU:
E-AB-92994
Additional Names:
ABC21,ABCB4,GBD1,ICP3,MDR2,MDR2/3,MDR3,PFIC-3,PGY3
Application:
WB
Concentration:
1 mg/ml
Purification:
Affinity Purified
Storage Conditions:
-20[o]C Avoid freeze/thaw cycles.
Supplier:
Elabscience
Host:
Rabbit
Reactivities:
Human, Mouse
Buffer:
Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
Immunogen:
Recombinant fusion protein of human ABCB4
Uniprot:
P21439
Synonyms:
ABC21;ATP-binding cassette sub-family B member 4;ATP-binding cassette, sub-family B (MDR/TAP), member 4;GBD1;ICP3;MDR2;MDR2/3;MDR3;multidrug resistance protein 3;multiple drug resistance 3;P-glycoprotein 3;P-glycoprotein-3/multiple drug resistance-3;PFIC-3;PGY3;phosphatidylcholine translocator ABCB4
Extra Details:
The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MDR/TAP subfamily. Members of the MDR/TAP subfamily are involved in multidrug resistance as well as antigen presentation. This gene encodes a full transporter and member of the p-glycoprotein family of membrane proteins with phosphatidylcholine as its substrate. The function of this protein has not yet been determined, however, it may involve transport of phospholipids from liver hepatocytes into bile. Alternative splicing of this gene results in several products of undetermined function.
Shipping Conditions:
Blue Ice