PAR2 Polyclonal Antibody

Size

£195.30

Was £217.00

SKU:: E-AB-92914
Additional Names:: F2RL1,GPR11,PAR2
Application:: WB, IF
Concentration:: 1 mg/ml
Purification:: Affinity Purified
Storage Conditions:: -20[o]C Avoid freeze/thaw cycles.
Supplier:: Elabscience
Host:: Rabbit
Reactivities:: Human, Mouse, Rat
Buffer:: Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
Immunogen:: Recombinant fusion protein of human PAR2
Uniprot:: P55085
Synonyms:: coagulation factor II (thrombin) receptor-like 1;Coagulation factor II receptor-like 1;G-protein coupled receptor 11;GPR11;PAR2;protease-activated receptor 2;proteinase-activated receptor 2;thrombin receptor-like 1
Extra Details:: Coagulation factor II (thrombin) receptor-like 1 (F2RL1) is a member of the large family of 7-transmembrane-region receptors that couple to guanosine-nucleotide-binding proteins. F2RL1 is also a member of the protease-activated receptor family. It is activated by trypsin, but not by thrombin. It is activated by proteolytic cleavage of its extracellular amino terminus. The new amino terminus functions as a tethered ligand and activates the receptor. The F2RL1 gene contains two exons and is widely expressed in human tissues. The predicted protein sequence is 83% identical to the mouse receptor sequence.