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E-AB-92905

MED17 Polyclonal Antibody

Size

£195.30

Was £217.00

SKU:
E-AB-92905
Additional Names:
CRSP6,CRSP77,DRIP80,MED17,SRB4,TRAP80
Application:
WB
Concentration:
1 mg/ml
Purification:
Affinity Purified
Storage Conditions:
-20[o]C Avoid freeze/thaw cycles.
Supplier:
Elabscience
Host:
Rabbit
Reactivities:
Human, Mouse, Rat
Buffer:
Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
Immunogen:
Recombinant fusion protein of human MED17
Uniprot:
Q9NVC6
Synonyms:
activator-recruited cofactor 77 kDa component;ARC77;Cofactor required for Sp1 transcriptional activation subunit 6;cofactor required for Sp1 transcriptional activation, subunit 6, 77kDa;CRSP complex subunit 6;CRSP6;CRSP77;DRIP80;epididymis secretory sperm binding protein;Mediator complex subunit 17;mediator of RNA polymerase II transcription subunit 17;SRB4;thyroid hormone receptor-associated protein complex 80 kDa component;transcriptional coactivator CRSP77;TRAP80;vitamin D3 receptor-interacting protein complex 80 kDa component
Extra Details:
The activation of gene transcription is a multistep process that is triggered by factors that recognize transcriptional enhancer sites in DNA. These factors work with co-activators to direct transcriptional initiation by the RNA polymerase II apparatus. The protein encoded by this gene is a subunit of the CRSP (cofactor required for SP1 activation) complex, which, along with TFIID, is required for efficient activation by SP1. This protein is also a component of other multisubunit complexes e.g. thyroid hormone receptor-(TR-) associated proteins which interact with TR and facilitate TR function on DNA templates in conjunction with initiation factors and cofactors.
Shipping Conditions:
Blue Ice