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E-AB-92827

MR1 Polyclonal Antibody

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£195.30

Was £217.00

SKU:
E-AB-92827
Additional Names:
HLALS,MR1
Application:
WB, IF
Concentration:
1 mg/ml
Purification:
Affinity Purified
Storage Conditions:
-20[o]C Avoid freeze/thaw cycles.
Supplier:
Elabscience
Host:
Rabbit
Reactivities:
Human, Mouse, Rat
Buffer:
Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
Immunogen:
Recombinant fusion protein of human MR1
Uniprot:
Q95460
Synonyms:
Class I histocompatibility antigen-like protein;HLALS;major histocompatibility complex class I-related gene protein;major histocompatibility complex, class I-like sequence;MHC class I-like antigen MR-1;MHC class-I related-gene protein
Extra Details:
MAIT (mucosal-associated invariant T-cells) lymphocytes represent a small population of T-cells primarily found in the gut. The protein encoded by this gene is an antigen-presenting molecule that presents metabolites of microbial vitamin B to MAITs. This presentation may activate the MAITs to regulate the amounts of specific types of bacteria in the gut. Several transcript variants encoding different isoforms have been found for this gene, and a pseudogene of it has been detected about 36 kbp upstream on the same chromosome.
Shipping Conditions:
Blue Ice