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E-AB-92719

BMX Polyclonal Antibody

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£195.30

Was £217.00

SKU:
E-AB-92719
Additional Names:
BMX,ETK,PSCTK2,PSCTK3
Application:
WB
Concentration:
1 mg/ml
Purification:
Affinity Purified
Storage Conditions:
-20[o]C Avoid freeze/thaw cycles.
Supplier:
Elabscience
Host:
Rabbit
Reactivities:
Human, Mouse
Buffer:
Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
Immunogen:
Recombinant fusion protein of human BMX
Uniprot:
P51813
Synonyms:
bone marrow tyrosine kinase gene in chromosome X protein;BTK-like on X chromosome;cytoplasmic tyrosine-protein kinase BMX;epithelial and endothelial tyrosine kinase;ETK;Etk/Bmx cytosolic tyrosine kinase;NTK38;NTK38 tyrosine kinase;PSCTK2;PSCTK3
Extra Details:
This gene encodes a non-receptor tyrosine kinase belonging to the Tec kinase family. The protein contains a PH-like domain, which mediates membrane targeting by binding to phosphatidylinositol 3,4,5-triphosphate (PIP3), and a SH2 domain that binds to tyrosine-phosphorylated proteins and functions in signal transduction. The protein is implicated in several signal transduction pathways including the Stat pathway, and regulates differentiation and tumorigenicity of several types of cancer cells. Alternatively spliced transcript variants have been found for this gene.
Shipping Conditions:
Blue Ice