E-AB-92705
VASH1 Polyclonal Antibody
Size
£195.30
Was £217.00
- SKU:
- E-AB-92705
- Additional Names:
- KIAA1036,VASH1
- Application:
- WB
- Concentration:
- 1 mg/ml
- Purification:
- Affinity Purified
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Host:
- Rabbit
- Reactivities:
- Human, Mouse
- Buffer:
- Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
- Immunogen:
- Recombinant fusion protein of human VASH1
- Uniprot:
- Q7L8A9
- Synonyms:
- KIAA1036;TTCP 1;tubulin carboxypeptidase 1;tubulinyl-Tyr carboxypeptidase 1;tyrosine carboxypeptidase 1
- Extra Details:
- Tyrosine carboxypeptidase that removes the C-terminal tyrosine residue of alpha-tubulin, thereby regulating microtubule dynamics and function. Critical for spindle function and accurate chromosome segregation during mitosis since microtuble detyronisation regulates mitotic spindle length and postioning. Acts as an angiogenesis inhibitor: inhibits migration, proliferation and network formation by endothelial cells as well as angiogenesis. This inhibitory effect is selective to endothelial cells as it does not affect the migration of smooth muscle cells or fibroblasts.
- Shipping Conditions:
- Blue Ice