E-AB-92666
MASP1 Polyclonal Antibody
Size
£195.30
Was £217.00
- SKU:
- E-AB-92666
- Additional Names:
- 3MC1,CRARF,CRARF1,MAP1,MASP,MASP1,MASP3,MAp44,PRSS5,RaRF
- Application:
- WB
- Concentration:
- 1 mg/ml
- Purification:
- Affinity Purified
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Host:
- Rabbit
- Reactivities:
- Human, Mouse, Rat
- Buffer:
- Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
- Immunogen:
- A synthetic peptide of human MASP1
- Uniprot:
- P48740
- Synonyms:
- 3MC1;C4/C2 activating component of Ra-reactive factor;complement factor MASP-3;complement-activating component of Ra-reactive factor;CRARF;CRARF1;mannan binding lectin serine peptidase 1;mannan-binding lectin serine protease 1;mannose-associated serine protease 1;mannose-binding lectin-associated serine protease 1;mannose-binding protein-associated serine protease;MAP-1;MAP1;MAp44;MASP;MASP-3;MASP3;PRSS5;Ra-reactive factor serine protease p100;RaRF;serine protease 5
- Extra Details:
- This gene encodes a serine protease that functions as a component of the lectin pathway of complement activation. The complement pathway plays an essential role in the innate and adaptive immune response. The encoded protein is synthesized as a zymogen and is activated when it complexes with the pathogen recognition molecules of lectin pathway, the mannose-binding lectin and the ficolins. This protein is not directly involved in complement activation but may play a role as an amplifier of complement activation by cleaving complement C2 or by activating another complement serine protease, MASP-2. The encoded protein is also able to cleave fibrinogen and factor XIII and may may be involved in coagulation. A splice variant of this gene which lacks the serine protease domain functions as an inhibitor of the complement pathway. Alternate splicing results in multiple transcript variants.
- Shipping Conditions:
- Blue Ice