ABCG2 Polyclonal Antibody

Size

£195.30

Was £217.00

SKU:: E-AB-92664
Additional Names:: ABC15,ABCG2,ABCP,BCRP,BCRP1,BMDP,CD338,CDw338,EST157481,GOUT1,MRX,MXR,MXR-1,MXR1,UAQTL1
Application:: WB, IF
Concentration:: 1 mg/ml
Purification:: Affinity Purified
Storage Conditions:: -20[o]C Avoid freeze/thaw cycles.
Supplier:: Elabscience
Host:: Rabbit
Reactivities:: Human, Mouse, Rat
Buffer:: Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
Immunogen:: A synthetic peptide of human ABCG2
Uniprot:: Q9UNQ0
Synonyms:: ABC transporter;ABC15;ABCP;ATP-binding cassette transporter G2;ATP-binding cassette, sub-family G (WHITE), member 2 (Junior blood group);BCRP;BCRP1;BMDP;breast cancer resistance protein;broad substrate specificity ATP-binding cassette transporter ABCG2;CD338;CDw338;EST157481;GOUT1;mitoxantrone resistance-associated protein;MRX;multi drug resistance efflux transport ATP-binding cassette sub-family G (WHITE) member 2;MXR;MXR-1;MXR1;placenta specific MDR protein;placenta-specific ATP-binding cassette transporter;UAQTL1;urate exporter
Extra Details:: The membrane-associated protein encoded by this gene is included in the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the White subfamily. Alternatively referred to as a breast cancer resistance protein, this protein functions as a xenobiotic transporter which may play a major role in multi-drug resistance. It likely serves as a cellular defense mechanism in response to mitoxantrone and anthracycline exposure. Significant expression of this protein has been observed in the placenta, which may suggest a potential role for this molecule in placenta tissue. Multiple transcript variants encoding different isoforms have been found for this gene.

Shipping Conditions:: Blue Ice