NMNAT1 Polyclonal Antibody

Size

£195.30

Was £217.00

SKU:: E-AB-92620
Additional Names:: LCA9,NMNAT,NMNAT1,PNAT1
Application:: WB
Concentration:: 1 mg/ml
Purification:: Affinity Purified
Storage Conditions:: -20[o]C Avoid freeze/thaw cycles.
Supplier:: Elabscience
Host:: Rabbit
Reactivities:: Human
Buffer:: Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
Immunogen:: Recombinant fusion protein of human NMNAT1
Uniprot:: Q9HAN9
Synonyms:: LCA9;NaMN adenylyltransferase 1;nicotinamide mononucleotide adenylyltransferase 1;Nicotinamide-nucleotide adenylyltransferase 1;nicotinamide/nicotinic acid mononucleotide adenylyltransferase 1;nicotinate-nucleotide adenylyltransferase 1;NMN adenylyltransferase 1;NMN/NaMN adenylyltransferase 1;NMNAT;PNAT1;pyridine nucleotide adenylyltransferase 1;SHILCA
Extra Details:: This gene encodes an enzyme which catalyzes a key step in the biosynthesis of nicotinamide adenine dinucleotide (NAD). The encoded enzyme is one of several nicotinamide nucleotide adenylyltransferases, and is specifically localized to the cell nucleus. Activity of this protein leads to the activation of a nuclear deacetylase that functions in the protection of damaged neurons. Mutations in this gene have been associated with Leber congenital amaurosis 9. Alternative splicing results in multiple transcript variants. Pseudogenes of this gene are located on chromosomes 1, 3, 4, 14, and 15.