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E-AB-92576

CD141/Thrombomodulin Polyclonal Antibody

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£195.30

Was £217.00

SKU:
E-AB-92576
Additional Names:
AHUS6,BDCA3,CD141,THBD,THPH12,THRM,TM
Application:
IHC, WB, IF
Concentration:
1 mg/ml
Purification:
Affinity Purified
Storage Conditions:
-20[o]C Avoid freeze/thaw cycles.
Supplier:
Elabscience
Host:
Rabbit
Reactivities:
Human, Mouse, Rat
Buffer:
Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
Immunogen:
Recombinant fusion protein of human CD141/Thrombomodulin
Uniprot:
P07204
Synonyms:
AHUS6;BDCA-3;BDCA3;CD141;CD141 antigen;fetomodulin;THPH12;THRM;thrombomodulin;TM
Extra Details:
The protein encoded by this intronless gene is an endothelial-specific type I membrane receptor that binds thrombin. This binding results in the activation of protein C, which degrades clotting factors Va and VIIIa and reduces the amount of thrombin generated. Mutations in this gene are a cause of thromboembolic disease, also known as inherited thrombophilia.
Shipping Conditions:
Blue Ice