E-AB-92469
PRMT6 Polyclonal Antibody
Size
£285.30
Was £317.00
- SKU:
- E-AB-92469
- Additional Names:
- HRMT1L6,PRMT6
- Application:
- WB, IF
- Concentration:
- 1 mg/ml
- Purification:
- Affinity Purified
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Host:
- Rabbit
- Reactivities:
- Human
- Buffer:
- Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
- Immunogen:
- Recombinant fusion protein of human PRMT6
- Uniprot:
- Q96LA8
- Synonyms:
- heterogeneous nuclear ribonucleoprotein methyltransferase-like protein 6;histone-arginine N-methyltransferase PRMT6;HMT1 hnRNP methyltransferase-like 6;HRMT1L6;protein arginine N-methyltransferase 6
- Extra Details:
- The protein encoded by this gene belongs to the arginine N-methyltransferase family, which catalyze the sequential transfer of methyl group from S-adenosyl-L-methionine to the side chain nitrogens of arginine residues within proteins, to form methylated arginine derivatives and S-adenosyl-L-homocysteine. This protein can catalyze both, the formation of omega-N monomethylarginine and asymmetrical dimethylarginine, with a strong preference for the latter. It specifically mediates the asymmetric dimethylation of Arg2 of histone H3, and the methylated form represents a specific tag for epigenetic transcriptional repression. This protein also forms a complex with, and methylates DNA polymerase beta, resulting in stimulation of polymerase activity by enhancing DNA binding and processivity.
- Shipping Conditions:
- Blue Ice