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E-AB-92384

OCRL Polyclonal Antibody

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£195.30

Was £217.00

SKU:
E-AB-92384
Additional Names:
INPP5F, LOCR, NPHL2, OCRL, OCRL-1, OCRL1, inositol polyphosphate-5-phosphatase,OCRL
Application:
WB
Concentration:
1 mg/ml
Purification:
Affinity Purified
Storage Conditions:
-20[o]C Avoid freeze/thaw cycles.
Supplier:
Elabscience
Host:
Rabbit
Reactivities:
Human
Buffer:
Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
Immunogen:
Recombinant fusion protein of human OCRL
Uniprot:
Q01968
Synonyms:
Dent-2;DENT2;inositol polyphosphate 5-phosphatase OCRL;inositol polyphosphate 5-phosphatase OCRL-1;INPP5F;LOCR;Lowe oculocerebrorenal syndrome protein;NPHL2;OCRL-1;OCRL1;oculocerebrorenal syndrome of Lowe;phosphatidylinositol 3,4,5-triphosphate 5-phosphatase;phosphatidylinositol polyphosphate 5-phosphatase
Extra Details:
This gene encodes an inositol polyphosphate 5-phosphatase. This protein is involved in regulating membrane trafficking and is located in numerous subcellular locations including the trans-Golgi network, clathrin-coated vesicles and, endosomes and the plasma membrane. This protein may also play a role in primary cilium formation. Mutations in this gene cause oculocerebrorenal syndrome of Lowe and also Dent disease. Alternate splicing results in multiple transcript variants.
Shipping Conditions:
Blue Ice