Placental alkaline phosphatase (PLAP) Polyclonal Antibody

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£195.30

Was £217.00

SKU:: E-AB-92361
Additional Names:: ALP, PALP, PLAP, PLAP-1, alkaline phosphatase, placental,ALPP
Application:: WB, IP
Concentration:: 1 mg/ml
Purification:: Affinity Purified
Storage Conditions:: -20[o]C Avoid freeze/thaw cycles.
Supplier:: Elabscience
Host:: Rabbit
Reactivities:: Human
Buffer:: Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
Immunogen:: Recombinant fusion protein of human Placental alkaline phosphatase
Uniprot:: P05187
Synonyms:: alkaline phosphatase Regan isozyme;alkaline phosphatase, placental type;alkaline phosphomonoesterase;ALP;ALPI;glycerophosphatase;IAP;Intestinal alkaline phosphatase;Intestinal-type alkaline phosphatase;PALP;placental alkaline phosphatase 1;PLAP;PLAP-1
Extra Details:: The protein encoded by this gene is an alkaline phosphatase, a metalloenzyme that catalyzes the hydrolysis of phosphoric acid monoesters. It belongs to a multigene family composed of four alkaline phosphatase isoenzymes. The enzyme functions as a homodimer and has a catalytic site containing one magnesium and two zinc ions, which are required for its enzymatic function. The protein is primarily expressed in placental and endometrial tissue, however, strong ectopic expression has been detected in ovarian adenocarcinoma, serous cystadenocarcinoma, and other ovarian cancer cells.